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Alpha GPC vs CDP Choline – Which One Is Better for Your Brain?

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Effortless Genius


“Success is something you attract by the person you become.”
—Jim Rogan

Unlike other nootropic compounds, Alpha GPC and CDP Choline aren’t the less discussed ones you can find out there. Yet, there’s some debate over which one is better. As you grow more concerned for your physical and mental wellbeing, these supplements play a big role in maintaining proper brain function and ensure your nervous system is armed with just the right nutrients to bear the hectic lifestyle. So here it is, the clash of Alpha GPC vs CDP Choline arrived, finally.

The Basics

We all have heard as children of the wide range of benefits liver and other organs offer to the body. In fact, eating the liver has played a huge role in enhancing your brain condition and reducing the malfunctions in your nervous system. This is because it is rich in choline.

Likewise, Alpha-GPC is available as a dietary supplement to help boost cognitive function and decrease the chances of Alzheimer’s disease.

So, what’s the difference between them and, most importantly, which one is better for you. Here’s an in-depth guide to answer all the swarming questions about Alpha GPC versus CDP Choline to help you make the right decision for yourself.

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What is Alpha GPC

“Invest in your dreams. Grind now. Shine later.”
– Unknown

Alpha GPC is a phospholipid essential for improving your brain health, boosting myeline production, and offering choline for cell membranes. This means you get to nourish your nervous system.

This supplement works by improving the blood flow to your brain and increasing a chemical in the brain called acetylcholine, which can otherwise cause health issues like strokes, Alzheimer’s disease, or dementia, when present in insufficient quantities. With this, you can also help enhance learning and memory skills.

Benefits of Alpha GPC

As you must have already figured, Alpha GPC is armed with a wide myriad of benefits to improve your overall health. However, what it is especially known for is its ability to improve brain and cognitive function. Not just that, here are some of the other benefits you can avail of from incorporating Alpha GPC into your regular diet.

Alzheimer’s Disease: During Alzheimer’s disease, countless mutated proteins kill neurons and deplete acetylcholine, causing you to drown in cognitive issues. However, a clinical trial conducted on 260 patients out of Switzerland and published in Molecules showed that Alpha GPC could delay Alzheimer’s disease and boost nootropic effects in younger people [1].

Cognitive Impairment and Dementia: Many older people frequently suffer from memory and cognitive decline. This is mainly the result of poor blood flow to your brain. Luckily, Alpha GPC can trigger just the right chemicals to help speed up the process of your blood flow to the brain.

Enhance Athletic Performance: Alpha-GPC has been a well-known supplement among many bodybuilding and athletes. But, that’s not it; it has been proven that taking Alpha GPC pre-workout can cause a growth hormone increase of up to a staggering 44% and increase bench press output by 14% as researchers showed in an articles published in the Journal of International Society of Sports and Nutrition [2]. The best part, you get a speedy recovery in no time.

Enhanced Focus: Struggling to stay concentrated in your work or school activities? Alpha-GPC can be your knight in shining armor. It can help strengthen concentration and focus on improving overall endurance and brain functionality.

Memory Enhancement: Although we have mentioned this point before, it needed more emphasis to help you get a proper idea. Alpha-GPC has been found effective against many memory disorders like Alzheimer’s, stroke, and vascular dementia.

Physical Strength: The Alpha-GPC offered by Marco’s Grounds is extracted to 99% purity to offer you a wide spectrum of benefits and increase physical performance and recovery.

Eyesight: The main reason behind poor eyesight is Ocular Ischemic Syndrome which occurs when plaque clogs the tiny blood vessels in the eye. This will not only lead to poor eyesight but can also be quite painful to go through. With Alpha GPC, you get to recover your retina and sharpen your vision in a relatively short span of time.

What is CDP Choline

“Great things are done by a series of small things brought together”
– Vincent Van Gogh

Citicoline, or also known as CDP choline, is a powerful compound that comes with neuroprotective properties to help transport dopamine and boost its release into your brain. Citicoline is made up of choline and cytidine. Choline can aid brain function, it is useful once it is converted into uridine. While cytidine can increase memory and focus.

The great thing about CDP Choline is how extremely safe and powerful it is when combined with other supplements. Therefore, you are unlikely to see it as a standalone supplement for improving neurotransmitters among cognitive and muscle functions.

Besides that, not only can CDP Choline be consumed with dietary supplements, but it can also be found in natural sources like eggs, whole grains, soybeans, chicken, and beef liver.

Benefits of CDP Choline

Just like Alpha GPC, CDP Choline also mainly offers benefits to your brain. This is one of the many reasons why they are two misunderstood supplements among enthusiasts. In particular, choline focuses primarily on combating distractions, aiding better focus and concentration in people.

At the cellular level, you may find CDP Choline improves neuronal membrane integrity and leads to a reduction in cases of neural death. Apart from that, here are some of the benefits you can expect from CDP Choline.

Nootropics: As a general rule of thumb, CDP Choline supplements contain other cognitive-enhancing ingredients called nootropics or cognitive enhancers that come with their own set of perks for your mental health. Nootropics can be found in omegas 3s, mushrooms, and herbs, which are some of the powerful foods needed to boost brain health. By consuming CDP Choline supplements, you get to cut down the hassle of keeping up with these foods and ensure you get enough essential nutrition.

Inositol: Most choline supplements also come with inositol, also known as B8, to regulate brain health and decrease signs of depression and anxiety. Many people over the years have also been counting on Inositol to fight PCOS and other fertility issues.

Combats Aging: A lesser-known benefit of CDP Choline is that the acetylcholine that it produces is also considered an anti-aging neurotransmitter to eliminate the drawbacks aging has on our bodies.

Aids Depression: There has been evidence proving that consuming CDP Choline has anti-depressive properties to help depression better than citalopram alone.

Boosting Metabolism: The speed at which your body burns calories and digest food plays a significant role in determining how fast or slow your gain or lose weight. Therefore, it is essential to keep your diet rich in high metabolism-boosting foods.

Research published in the Journal of human kinetics has found that female athletes who have been rigorous with choline supplements tend to have lower masses of body mass indexes (BMIs) and leptin (body fat) levels than others [3].

Alpha GPC versus CDP Choline: Difference

“Without great solitude, no serious work is possible.”
— Pablo Picasso

Nothing is more embarrassing than forgetting the names of people at a party. Just imagine introducing someone, and you don’t remember their name or where you met them in the first place. That’s where Alpha GPC and CDP Choline come into the picture.

But what’s the difference, we hear you ask?

Now that you are aware of the fundamentals of both supplements, you must have noticed minimal to no difference among them. If yes, you aren’t alone.

At a glance, they both seem to offer the same uses and benefits for your brain health. However, there are a few differences that one has the upper hand over the other. For example, both alpha GPC and CDP Choline offer different metabolism processors. This is what releases as a byproduct.

There are many benefits Alpha GBC offers that CDP Choline doesn’t, and vice versa. Here, Alpha GPC could lead to improved vitality and strength to help your muscles recover effectively after exercise. It can also boost the production of growth hormones in the human body while maintaining brain energy high.

While CDP Choline also comes with benefits that you are unlikely to see in Alpha GPC. One well-known perk is its amplified nootropics benefits that can make it a must-have in your regular diet (great to combine with Taurine to multiply the effects of other nootropics further)

So, when deciding between Alpha GPC versus CDP Choline, it really comes to personal preference. One works well by enhancing the lost nutrients in your brain; the other does wonder by eliminating the distracting factors in your body.

If you are unsure of the best one, it’s never a bad idea to try out both and pick the one that works best for you. Yet the truth is that both work well and especially so when combined in the proper ratio like Marco’s Grounds does with MAXIMUM MIND®.

Why Are They Important

“It’s not the load that breaks you down, it’s the way you carry it.”
– Lou Holtz

Alpha GPC and CDP Choline are two of the essential supplements to enhance the quality of your life. However, unlike others, you don’t really get to hear many stories about these two. So why would you go for these instead of the conventional vitamins and dietary supplements?

Glad you asked.

Here’s why Alpha GPC and CDP Choline are essential.

Reduces Pregnancy Complications

A lot goes into making these supplements. They work by eliminating the root cause of significant problems and bringing back the lost minerals to your body. Here, Choline can affect the fetal development of women, which, as a result, can influence your pregnancy journey.

Most of the women who consume 480 milligrams (mg) of choline per day have noticed reduced symptoms of pregnancy complications like severe headaches, swelling, and high blood pressure, as a study published in Nutrients suggests [4].

This means by incorporating Alpha GPC and CDP Choline into your diet, you don’t just ensure excellent brain health but also improve the life of your new bundle of joy.

Dementia, Brain Health, and Mental Performance

Dementia is a word used to describe a wide range of problems associated with mental functioning. These include forgetfulness, difficulty in problem-solving, communication issues, etc.

Dementia is a progressive problem that begins with having little to no effect in your regular life to gradually increasing and becoming the biggest obstacle you must face to go through each second of the day.

This condition is so common that it affects one in three individuals over 65 years old who fail to enjoy their life to the fullest after dementia strikes them. Luckily, by adopting healthy habits from an earlier age, including supplements containing Alpha GPC and CDP Choline, you get to reduce the risk of brain damage and improve your quality of life with time.

This way, you get to make the most out of your life after retirement.

Live an Active Life

Improving your brain functioning isn’t just associated with mental health. But it can also play a big hand in controlling your physical behaviors and make you active in everyday life. For example, as Alpha GPC and CDP Choline can regulate blood flow, you can rest assured to have a supportive body during workouts and recover faster to help you begin the next active journey.

Help Maintain a Balanced Diet

Are you struggling to maintain a healthy diet? These can help.

The freshly chosen ingredients help protect your brain using the right blend to create a balanced diet to ensure you get an extra boost of sources from this supplement as well. With this, you can remain healthy by eliminating brain fog signs, increasing speed of thought, and supporting cognitive functions.

All in all, Alpha GPC is a choline-containing supplement that is ideal for boosting acetylcholine in the brain and defeating age-related cognitive dementia and decline. As a result, many younger people have seen tremendous benefits to enhance cognition and improve overall physical performance.

MAXIMUM MIND® provides Citicoline as Cognizin® coupled with premium Alpha GPC and Uridine, so your brain is supplied with all significant choline donors.

That said, MAXIMUM MIND® is everything you need in an ideal supplement that helps you focus on complex tasks, react quicker, remember names, learn new concepts better, and boost other cognitive abilities to help you win over anything you have in mind.

MAXIMUM MIND® is known to bridge the gap between your goals and focus on helping you devote yourself to a mission and ensure no obstacle comes your way.



Clinically Studied

Pharmaceutical Grade Cognitive and Mind Enhancing Complex
Made in Switzerland


  1. Kumar, H., More, S. V., Han, S. D., Choi, J. Y., & Choi, D. K. (2012). Promising therapeutics with natural bioactive compounds for improving learning and memory–a review of randomized trials. Molecules (Basel, Switzerland), 17(9), 10503–10539.
  2. Ziegenfuss, T., Landis, J. & Hofheins, J. Acute supplementation with alpha-glycerylphosphorylcholine augments growth hormone response to, and peak force production during, resistance exercise. J Int Soc Sports Nutr 5, P15 (2008).
  3. Elsawy, G., Abdelrahman, O., & Hamza, A. (2014). Effect of choline supplementation on rapid weight loss and biochemical variables among female taekwondo and judo athletes. Journal of human kinetics, 40, 77–82.
  4. Korsmo, H. W., Jiang, X., & Caudill, M. A. (2019). Choline: Exploring the Growing Science on Its Benefits for Moms and Babies. Nutrients, 11(8)

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The materials and information provided in this post, document and/or any other communication (“Communication”) from Marco’s Grounds LLC. or any related entity or person (collectively “Marco’s Grounds”) are strictly for informational purposes only and are not intended for use as diagnosis, prevention or treatment of a health problem or as a substitute for consulting a qualified medical professional. Some of the concepts presented herein may be theoretical.

References to any non-Marco’s Grounds entity, product, service, person or source of information in this or any other Communication should not be considered an endorsement, either direct or implied, by the host, presenter or distributor of the Communication. The host(s), presenter(s) and/or distributor(s) of this Communication are not responsible for the content of any non-Marco’s Grounds internet pages referenced in the Communication. Marco’s Grounds is not liable or responsible for any advice, course of treatment, diagnosis or any other information or services you chose to follow without consulting a qualified medical professional. Before starting any new diet and/or exercise program, always be sure to check with your qualified medical professional.

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