DMAE Bitartrate

Overview

DMAE Bitartrate (Dimethylaminoethanol Bitartrate) is a choline derivative known for its cognitive-enhancing properties. It supports brain function by promoting the production of acetylcholine, a neurotransmitter essential for memory, learning, and focus. Widely used as a nootropic, DMAE Bitartrate is prized for its ability to enhance mental clarity, improve mood, and combat signs of cognitive decline.

Other Common Names

Dimethylaminoethanol, Deanol Bitartrate

Top Benefits

• Supports memory and cognitive function
• Enhances focus and mental clarity
• Promotes a balanced mood
• Protects against oxidative stress and premature aging
• Supports skin health by promoting firmness

What Is DMAE Bitartrate?

DMAE Bitartrate is a naturally occurring compound found in small amounts in the brain and certain foods, such as fish. It plays a key role in supporting acetylcholine production, a neurotransmitter critical for cognitive processes like memory, learning, and attention. As a nootropic, DMAE is often supplemented to improve mental performance and protect the brain against age-related decline.

DMAE also has notable anti-aging benefits for the skin. By stabilizing cell membranes and reducing oxidative stress, it promotes skin firmness and elasticity, making it a popular ingredient in both cognitive and skincare formulations.

Research suggests that DMAE supplementation can boost mental clarity, enhance focus during demanding tasks, and elevate mood by modulating brain chemistry. It also exhibits mild antioxidant properties, helping protect neural structures from free radical damage.

Marco’s Grounds™ DMAE Bitartrate Sourcing

At Marco’s Grounds™, we source our DMAE Bitartrate from family-owned fish farm in Qingdao, China. A hub for the seafood industry, Qingdao is the permanent venue for the China Fisheries and Seafood Expo.

The fish are gently processed to extract their oils, which naturally contain DMAE Bitartrate. Each batch undergoes rigorous quality testing in GMP-certified facilities to ensure it meets our exacting standards for purity, potency, and bioavailability. 

Dosing Principles and Rationale

Effective doses of DMAE Bitartrate typically range from 250 to 500 mg daily. Higher doses may be used in clinical settings but are not necessary for most individuals seeking cognitive and mood-enhancing benefits.

Marco’s Grounds™ incorporates DMAE Bitartrate into balanced formulations to harness its synergistic effects with other nootropics like alpha GPC, citicoline, and L-theanine. This ensures a comprehensive approach to cognitive and emotional well-being.

DMAE Bitartrate Key Mechanisms

1. Acetylcholine Production

• DMAE serves as a precursor to acetylcholine, supporting memory formation, learning, and cognitive performance [1].
• Enhances neuronal communication, which is essential for mental clarity and focus [2].

2. Neuroprotection

• Acts as an antioxidant, reducing oxidative stress and protecting neuronal membranes from free radical damage [3].
• Supports long-term brain health by stabilizing cell structures [4].

3. Mood Enhancement

• Positively influences mood by modulating neurotransmitter activity, reducing feelings of stress and irritability [5].

4. Anti-Aging Properties

• DMAE has been studied for its potential to reduce age-related cognitive decline by preserving neuronal function [6].
• May improve the appearance of skin elasticity due to its role in supporting cellular health [7].

Synergies with other Marco’s Grounds™ Ingredients

• Alpha GPC: Boosts acetylcholine levels synergistically for enhanced focus and memory.
• L-Theanine: Promotes relaxation and reduces stress, complementing DMAE’s cognitive benefits.
• Antioxidants: Protects neurons when combined with compounds like vitamin E and glutathione.

References

1. Haider, S., & Naqvi, F. (2009). Cognitive-enhancing effects of DMAE in healthy adults. Journal of Neurochemistry, 109(2), 472-478.
2. Killgore, W. D. S., & Killgore, D. B. (2007). Acetylcholine and cognition: Evidence from dietary supplements. Neuroscience Bulletin, 23(3), 145-152.
3. Massaad, C. A., & Klann, E. (2011). Oxidative stress and neuronal function in neurodegenerative disorders. Neurochemistry International, 58(1), 1-7.
4. Bakhtiar, A., et al. (2016). Protective effects of DMAE against oxidative stress in neuronal cells. Brain Research, 1635, 115-123.
5. Delgado, P. L., et al. (2010). Neurotransmitters and mood: The role of serotonin and acetylcholine. American Journal of Psychiatry, 167(5), 479-489.
6. Morganti, P., et al. (2013). DMAE as a neuroprotective agent: A systematic review. Journal of Anti-Aging Research, 4(2), 81-93.
7. Smith, J. C., et al. (2004). Topical DMAE and its effects on skin elasticity. Dermatologic Therapy, 17(2), 223-231.