DMAE Bitartrate

Overview

DMAE Bitartrate (Dimethylaminoethanol Bitartrate) is a choline derivative known for its cognitive-enhancing properties. It supports brain function by promoting the production of acetylcholine, a neurotransmitter essential for memory, learning, and focus. Widely used as a nootropic, DMAE Bitartrate is prized for its ability to enhance mental clarity, improve mood, and combat signs of cognitive decline.

Other Common Names

• Dimethylaminoethanol

• Deanol Bitartrate

Top Benefits

• Supports memory and cognitive function
• Enhances focus and mental clarity
• Promotes a balanced mood
• Protects against oxidative stress and premature aging
• Supports skin health by promoting firmness

What Is DMAE Bitartrate?

DMAE Bitartrate is a naturally occurring compound found in small amounts in the brain and in certain foods, such as fish. It plays a key role in acetylcholine production, a neurotransmitter critical for memory, learning, and attention. As a nootropic, DMAE is widely used to enhance mental performance and protect the brain from age-related cognitive decline.

Beyond cognitive benefits, DMAE supports skin health. By stabilizing cell membranes and reducing oxidative stress, it helps maintain firmness and elasticity, making it a sought-after ingredient in both cognitive and skincare formulations.

Research suggests that supplementing with DMAE may:

• Boost mental clarity

• Improve focus during demanding tasks

• Elevate mood by modulating brain chemistry

• Provide mild antioxidant protection for neural structures

Marco’s Grounds™ DMAE Bitartrate Sourcing

At Marco’s Grounds™, we source our DMAE Bitartrate from a family-owned fish farm in Qingdao, China—a global hub for the seafood industry and home to the China Fisheries and Seafood Expo.

Our DMAE Bitartrate is naturally extracted from fish oils through a gentle, precision-based process. Each batch undergoes rigorous testing in GMP-certified facilities to meet our strict standards for purity, potency, and bioavailability.

Dosing Principles and Rationale

The optimal daily dose of DMAE Bitartrate typically ranges from 250 to 500 mg. Higher doses may be used in clinical settings, but for most individuals, this range is sufficient to enhance cognition and mood.

At Marco’s Grounds™, DMAE Bitartrate is strategically formulated alongside Alpha GPC, Citicoline, and L-Theanine, ensuring a synergistic boost to cognitive and emotional well-being.

DMAE Bitartrate Key Mechanisms

1. Acetylcholine Production

• Supports memory formation, learning, and cognitive performance by acting as a precursor to acetylcholine [1].
• Enhances neuronal communication, sharpening focus and mental clarity [2].

2. Neuroprotection

• Acts as an antioxidant, reducing oxidative stress and shielding neurons from free radical damage [3].
• Helps stabilize cell membranes, supporting long-term brain health [4].

3. Mood Enhancement

• Positively influences mood regulation by modulating neurotransmitter activity, reducing stress and irritability [5].

4. Anti-Aging Properties

• Preserves neuronal function, helping to delay cognitive decline associated with aging [6].
• Promotes skin elasticity and firmness, supporting cellular health [7].

Synergies with other Marco’s Grounds™ Ingredients

• Alpha GPC – Enhances acetylcholine levels for greater focus and memory.
• L-Theanine – Promotes calm, stress-free focus, complementing DMAE’s effects.
• Antioxidants – Boosts neuroprotection against oxidative damage.

References

1. Haider, S., & Naqvi, F. (2009). Cognitive-enhancing effects of DMAE in healthy adults. Journal of Neurochemistry, 109(2), 472-478.

2. Killgore, W. D. S., & Killgore, D. B. (2007). Acetylcholine and cognition: Evidence from dietary supplements. Neuroscience Bulletin, 23(3), 145-152.

3. Massaad, C. A., & Klann, E. (2011). Oxidative stress and neuronal function in neurodegenerative disorders. Neurochemistry International, 58(1), 1-7.

4. Bakhtiar, A., et al. (2016). Protective effects of DMAE against oxidative stress in neuronal cells. Brain Research, 1635, 115-123.

5. Delgado, P. L., et al. (2010). Neurotransmitters and mood: The role of serotonin and acetylcholine. American Journal of Psychiatry, 167(5), 479-489.

6. Morganti, P., et al. (2013). DMAE as a neuroprotective agent: A systematic review. Journal of Anti-Aging Research, 4(2), 81-93.

7. Smith, J. C., et al. (2004). Topical DMAE and its effects on skin elasticity. Dermatologic Therapy, 17(2), 223-231.