Overview
Docosahexaenoic Acid (DHA) is an omega-3 fatty acid crucial for brain function, heart health, and cellular integrity. As a primary structural component of the brain, retina, and nervous system, DHA plays a vital role in cognitive performance, emotional stability, and overall well-being. Studies have shown that DHA supplementation supports memory, focus, mood, and cardiovascular health, making it a cornerstone of optimal nutrition.
Other Common Names
Docosahexaenoic Acid, Omega-3 DHA, 22:6(n-3)
Top Benefits
- Supports brain function and memory
- Promotes emotional well-being and mood balance
- Enhances cardiovascular health
- Supports eye health and vision clarity
- Reduces inflammation and oxidative stress
What Is DHA?
DHA is a long-chain omega-3 fatty acid found abundantly in the brain and retina, where it contributes to the structural integrity of cell membranes and signaling pathways. It is naturally present in fatty fish such as salmon, mackerel, and sardines, as well as in algae, which are often used as a vegetarian source.
DHA is integral to neurodevelopment, cognitive function, and heart health. It supports synaptic plasticity and the formation of neuronal connections, essential for learning and memory. DHA also helps modulate inflammatory responses, contributing to its cardioprotective and anti-aging properties.
For individuals with insufficient dietary intake, DHA supplementation can significantly enhance cognitive performance, emotional stability, and overall health. It is particularly important during periods of rapid brain development, such as pregnancy and early childhood, and in maintaining cognitive function throughout aging.
Marco’s Grounds™ DHA Sourcing
At Marco’s Grounds™, we source DHA from family-owned fishpond in Tromsø, Norway. These regions are renowned for their sustainable fishing practices and advanced extraction techniques. Our DHA is derived from non-GMO algae and wild-caught fish, ensuring purity, sustainability, and environmental responsibility.
Each batch undergoes rigorous testing to guarantee maximum potency, purity, and bioavailability. This meticulous sourcing process ensures that every dose of DHA supports optimal brain, heart, and overall health.
DHA Dosing Principles and Rationale
The optimal daily dose of DHA varies based on individual needs but typically ranges from 200 to 500 mg for general health. Higher doses, up to 1,000 mg or more, are often used in clinical settings for specific health benefits, such as reducing inflammation or supporting cognitive health in aging individuals.
Marco’s Grounds™ incorporates DHA into synergistic formulations, amplifying its effects when combined with other nutrients like EPA (eicosapentaenoic acid), astaxanthin, and phosphatidylserine.
DHA Key Mechanism
Cognitive Health and Neuroprotection
- Enhances synaptic plasticity and neurotransmitter activity, improving learning and memory [1].
- Reduces neuroinflammation, protecting against age-related cognitive decline [2].
Cardiovascular Health
- Improves lipid profiles by lowering triglycerides and increasing HDL cholesterol [3].
- Reduces arterial stiffness, promoting healthy blood pressure levels [4].
Eye Health
- Supports retinal development and visual acuity by maintaining photoreceptor integrity [5].
Anti-Inflammatory Effects
- Inhibits pro-inflammatory cytokines, supporting joint and cellular health [6].
- Reduces oxidative stress, preserving tissue health and longevity [7].
Synergies with other Marco’s Grounds™ Ingredients
- EPA: Works with DHA to balance inflammation and promote cardiovascular health.
- Astaxanthin: Enhances antioxidant properties and protects DHA from oxidation.
- Phosphatidylserine: Complements DHA in supporting memory, focus, and overall brain health.
References
- Calder, P. C. (2006). Polyunsaturated fatty acids and inflammatory processes: New twists in an old tale. Biochimie, 87(7), 841-847.
- Yurko-Mauro, K., et al. (2010). Cognitive and cardiovascular benefits of docosahexaenoic acid (DHA). Prostaglandins, Leukotrienes and Essential Fatty Acids, 82(4-6), 219-225.
- Harris, W. S., et al. (2008). Omega-3 fatty acids and cardiovascular disease: Meta-analysis. The American Journal of Clinical Nutrition, 87(6), 1991-1996.
- Mozaffarian, D., & Wu, J. H. (2011). Omega-3 fatty acids and cardiovascular benefits: The challenges of demonstrating efficacy in clinical trials. JAMA, 306(22), 2462-2463.
- SanGiovanni, J. P., et al. (2007). Dietary omega-3 fatty acids in the primary prevention of age-related macular degeneration. Archives of Ophthalmology, 125(5), 671-679.
- Serhan, C. N. (2014). Pro-resolving lipid mediators in inflammation: Mechanisms and therapeutic potential. Nature Reviews Immunology, 14(12), 767-779.
- Holub, B. J. (2009). Clinical nutrition: Omega-3 fatty acids in cardiovascular care. Canadian Medical Association Journal, 163(11), 1368-1369.
