Magnesium Glycinate

Overview

Magnesium is a vital mineral involved in over 300 enzymatic reactions in the body, making it essential for energy production, muscle function, and neurological health. Known as the “relaxation mineral,” magnesium plays a pivotal role in reducing stress, supporting restful sleep, and maintaining cardiovascular health.

Other Common Names

• Bisglycinate Magnesium
• Magnesium Diglycinate

Top Benefits

• Supports relaxation and stress reduction

• Improves sleep quality

• Promotes muscle recovery and reduces cramps

• Supports cardiovascular and bone health

• Boosts energy production and cellular function
  

What Is Magnesium Glycinate?

Magnesium is an essential mineral involved in over 300 biochemical processes in the body, including energy production, nerve function, and muscle relaxation. Magnesium Glycinate combines magnesium with glycine, a non-essential amino acid known for its calming effects, creating a highly absorbable form of magnesium with added relaxation benefits.

This unique form of magnesium is especially effective for promoting mental calmness, improving sleep, and reducing stress. Unlike other magnesium supplements, Magnesium Glycinate is less likely to cause gastrointestinal discomfort, making it ideal for those with sensitive stomachs.

Deficiencies in magnesium are common due to modern diets and soil depletion, leading to symptoms such as fatigue, muscle cramps, and poor sleep. Supplementing with Magnesium Glycinate provides a reliable, well-tolerated solution to restore optimal levels and promote whole-body wellness.

Marco’s Grounds™ Magnesium Glycinate Sourcing

At Marco’s Grounds™, our Magnesium Glycinate is sourced with a relentless focus on purity, bioavailability, and sustainability. We extract magnesium from salmon raised in a family-owned fishpond in Norway, then chelate it with glycine—an amino acid known for its calming effects—to create an exceptionally absorbable and gentle form of magnesium.

Every batch is subjected to rigorous quality control, ensuring it remains free from heavy metals, GMOs, and synthetic additives. The result: clean, effective support for relaxation, recovery, and total-body resilience — delivered with uncompromising precision in every dose.

Magnesium Glycinate Dosing Principles and Rationale

The recommended daily dose of Magnesium Glycinate ranges from 200 to 400 mg of elemental magnesium, depending on individual needs and goals. Marco’s Grounds™ applies hormetic dosing principles to find the optimal dosage — providing maximum benefit without exceeding the body's needs.

• For relaxation and sleep support, Magnesium Glycinate is best taken in the evening.

• For muscle recovery and general wellness, it can be taken with meals throughout the day.

Magnesium Glycinate Key Mechanisms

1. Relaxation and Stress Reduction

• Increases GABA activity in the brain, promoting calmness and mental ease [1].

• Regulates the HPA axis, moderating stress responses [2].

2. Sleep Quality

• Enhances melatonin production and nervous system calm, improving sleep duration and quality [3].

• Reduces nighttime cramps and restlessness for more restorative sleep [4].

3. Muscle and Recovery

• Balances calcium levels to prevent excessive muscle contractions and support muscle relaxation [5].

• Aids in energy metabolism and electrolyte balance, reducing soreness and improving recovery [6].

4. Cardiovascular and Bone Health

• Relaxes vascular smooth muscle to help lower blood pressure [7].

• Supports bone density by aiding calcium absorption and deposition [8].

Synergies with other Marco’s Grounds™ Ingredients

• Vitamin B6 – Enhances magnesium absorption and its calming effects.

• L-Theanine – Amplifies stress-relieving benefits and relaxation.

• Ashwagandha – Works synergistically to enhance stress resilience and support overall calmness.

References

1. Eby, G. A., & Eby, K. L. (2006). Rapid recovery from major depression using magnesium treatment. Medical Hypotheses, 67(2), 362–370.

2. Boyle, N. B., Lawton, C., & Dye, L. (2017). Effects of magnesium supplementation on anxiety and stress. Nutrients, 9(5), 429.

3. Abbasi, B., et al. (2012). Magnesium supplementation for primary insomnia in the elderly. Journal of Research in Medical Sciences, 17(12), 1161.

4. Romero, J. R., & Sanderson, W. C. (2000). Magnesium in muscle function and recovery. American Journal of Therapeutics, 7(4), 267–273.

5. de Baaij, J. H., et al. (2015). Magnesium in man: Implications for health and disease. Physiological Reviews, 95(1), 1–46.

6. Wester, P. O. (1987). Magnesium in clinical nutrition. American Journal of Clinical Nutrition, 45(5), 1305–1312.

7. Houston, M. (2011). Magnesium and cardiovascular disease. Journal of Clinical Hypertension, 13(11), 843–847.

8. Rude, R. K., & Shils, M. E. (2006). Magnesium. In Modern Nutrition in Health and Disease (10th ed., pp. 223–247).