Best Nootropics for Brain Fog

June 13, 2022

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Slow thinking, low motivation, a depressed mood, a shaky memory, and difficulty focusing are common conditions affecting the human brain. When brain fog sets in, it has the potential to impair nearly all facets of brain function. The good news is that the best nootropics for brain fog may be beneficial. 

With natural, healthy support for mental energy, brain chemistry, and stress resistance, the correct nootropics can help you overcome brain fog burnout and rejuvenate your entire cognitive function.

Without beating around the bush, the best nootropics for brain fog are; citicoline, N-acetyl L-tyrosine, methylated b vitamins, organic bacopa monnieri leaf extract, organic ashwagandha root extract, and uridine. These nootropics are bioavailable in their purest forms in MAXIMUM MIND. Continue reading to learn more about their benefits in preventing brain fog. 

This article examines the best nootropics for brain fog in regards to recovering mental clarity or preventing it.

“The real test is not whether you avoid this failure because you won’t. It’s whether you let it harden or shame you into inaction, or whether you learn from it; whether you choose to persevere.”
— Barack Obama

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“The only difference between the master and the novice is that the master has failed more times than the novice has tried.”
― Stephen McCranie

First things first, what are nootropics? Corneliu Giurgea, a Romanian neuroscientist, coined the term nootropic (pronounced new-tropic) in 1972. He believed that brain boosters should be invented and made widely available for the purpose of enhancing the general population’s brain health and increasing human intelligence.

According to Dr. Giurgea’s findings, nootropics or brain boosters enhance cognition, memory, alertness, concentration, creativity, and attention or simply put: brain function. They became known as cognitive enhancers, substances that amplify the way the brain’s many cognitive activities operate and how we process information.

Simply put, cognitive enhancers (or brain boosters or smart drugs) are prescription or off-the-counter drugs or supplements that enhance the cognition of the human brain. Some nootropics contribute to brain health, while others can be quite dangerous.

Since Marco’s Grounds only works with safe and natural nootropics in their purest forms, we will restrain ourselves to natural nootropics that increase cognition safely for most of our discussions.


What is Brain Fog?

“Don’t worry about being successful but work toward being significant and the success will naturally follow.”
— Oprah Winfrey

One study found in the Journal of Gastroenterology and Hepatology asserts that brain fog is a momentary loss of cognitive function and mental performance that is often manifested by a modest, transient impairment of memory or memory loss, attention, processing speed, and other executive processes. [1]

Brain fog, also known as mental exhaustion or burnout, frequently shows as a period of unexpected mental disorientation characterized by difficulty to focus, poor memory, and bewilderment. Brain fog is a common condition of the human brain.

This cognitive fog might be minor or severe, aggravating or completely incapacitating.

Brain fog may impair your clarity and productivity to varying degrees, and milder instances are easily dismissed.

You may encounter one or two isolated episodes as a result of your lifestyle choices, but if the fuzziness becomes more common, you may need to make some changes to prevent further impairments to brain activity.

man with bowler with cloud over his head

Brain Fog Symptoms

“The secret of your success is determined by your daily agenda.”
— John C Maxwell

Today is a momentous occasion. Your long-awaited presentation is planned for 2 p.m., and you’re revved up and ready to go. However, when you sit down to add the final touches, your mind goes blank.

You struggle to find the appropriate words. It should be simple, but you are unable to concentrate. It appears as though the words you’re seeking are just out of reach, yet the more determined you are to extract them, the more irritated you feel. What is happening?

You’ve almost certainly been struck by a severe case of brain fog.

A gradual, moderate reduction in cognitive abilities, particularly memory, is seen as a normal component of aging.

However, brain fog is not a typical feature of age-related cognitive loss and may indicate major physiological inadequacies or mental health problems.

Some of the symptoms of brain fog are similar to those of other diseases, such as attention deficit disorder (ADD) or attention deficit hyperactivity disorder (ADHD).

The primary distinction between brain fog and psychological or cognitive illnesses is that brain fog is often transient, whereas diseases are typically chronic or recurrent.

The symptoms of brain fog vary but may include trouble with the following cognitive activities :

  • learning
  • multitasking
  • math and numerical processing
  • mood
  • focus
  • working memory
  • spatial orientation
  • recalling words
  • depression
  • sluggish mental function

Additionally, some individuals report feeling lightheaded, dizzy, and in general “cloudy.”

As with other illnesses, brain fog symptoms are merely a symptom of an underlying problem that, if left untreated, can degrade mental performance further.


How Brain Fog Works

“Only those who dare to fail greatly can achieve greatly.” 
— Robert F. Kennedy

Although an extensive clinical trial found in Frontiers in Physiology has been conducted on the individual components of chronic fatigue’s cognitive symptoms, sources lack a full account of the numerous elements that contribute to brain fog and their interactions with brain cells. [2]

However, researchers are beginning to comprehend the structural alterations associated with brain fog’s cognitive symptoms by researching clinically diagnosed mental burnout, such as loss of creativity, difficulties with problem-solving, and poor working memory.

In a review of 15 very trustworthy pieces of research, a team of Greek experts confirmed that burnout was connected with cognitive abnormalities in 13 of the 15 investigations. 

According to the researchers, “burnout appears to affect executive attentional and memory processes, and brain activity is reduced in burned-out individuals.”

Prefrontal Cortex

The prefrontal cortex (PFC) is the brain area responsible for motor activities, learning behaviors, speech, and language. The PFC gradually thins as people age, and cognitive impairments become more obvious around the age of 60.

However, mental burnout-affected brains exhibit more thinning than usual in the medial prefrontal cortex (mPFC), regardless of age, as compared to control volunteers. This of course can have a detrimental effect on long-term brain health and mental performance.

A study found in Cerebral Cortex verifies that a thinner PFC results in fewer neuronal connections, smaller dendritic clusters, decreased synaptic transmission, and brain-derived neurotrophic factor (BDNF) production resulting in decreased cognitive performance and less efficient brain communication. [3]

Over time, brain supplements for BDNF may assist in mitigating the effects of stress-related brain fog.

Consequently, to quality as the best nootropics for brain fog a nootropic needs to increase or promote BDNF.


Mental burnout patients appear to have a bigger amygdala, a physical sign of recurrent stimulation caused by continuous, acute stress.

One study in Nature Reviews Neuroscience asserts that amygdala hyperactivity impairs mPFC modulation. This further excites the amygdala, which stimulates the mPFC, resulting in a downward spiral of overactivation in both the mPFC and the amygdala, prematurely “aging” them both. [4]

As this cycle continues, brain structures deteriorate, resulting in cortical thinning and difficulties with memory, attention, and emotional control.

Basal Ganglia

Ivanka Savic, a neurologist, and a Karolinska Institute stress researchers team discovered that chronic stress was associated with considerable gray matter loss in the hippocampus, caudate nucleus, and putamen.

A study in Cerebral Cortex found that these structures work in concert to govern learning and memory, and they are particularly vulnerable to neurotoxic alterations generated by excessive glutamate release in response to excessive oxidative stress or severe trauma. [5]

According to research found in Association for Psychological Science, “data from animal studies demonstrate that stress increases glutamate release and that an increase in extracellular glutamate levels associated with stress induces spine retraction in stress-targeted regions such as the mPFC, the anterior cingulate, and the basal ganglia.” [6]

Neuroimaging studies of individuals who have suffered severe trauma indicate brain patterns that are comparable to those suffering from clinical burnout. This study demonstrates that both acute trauma and accumulated stress can harm neural networks.


Fibromyalgia, Chronic Fatigue, and Fibro Fog

“The essential part of creativity is not being afraid to fail.” 
— Edwin Land

Fibro fog is a frequent symptom of fibromyalgia (FMS) and chronic fatigue syndrome (ME/CFS).

The fogginess associated with these disorders can be severe and prolonged and is frequently accompanied by discomfort or exhaustion. According to some patients, fibro fog is more incapacitating than other physical symptoms. Fatigue, worry, tension, and sensory overload all contribute to the aggravation of fibro fog.

Because the cognitive function is so complicated, it has been challenging to pinpoint the source of brain fog, but the current study provides some hints.

According to one study found in the International Journal of Quality of Life, those with FMS and ME/CFS had higher cognitive impairment than those who only have ME/CFS. In the study, individuals who experienced higher discomfort also had a harder time recalling spoken material. [7]

Another research in the Official Journal of the International Federation of Clinical Neurophysiology found that those with ME/CFS alone tended to have more trouble with visual perception. [8]

One of the most common symptoms of persons suffering from fibro fog or ME/CFS is trouble recalling words. Their statements are backed up by research, demonstrating that persons with FMS recall words more slowly than those with other memory problems. The smart drugs for verbal fluency, such as MAXIMUM MIND, can easily facilitate the brain’s ability to recall words easily. They are also one of the best nootropics for brain fog 


Life Impact of Brain Fog and Mental Burnout

“Little minds are tamed and subdued by misfortune, but great minds rise above them.” 
— Washington Irving

Burnout is a state of emotional, mental, and physical weariness that typically occurs due to continuous exposure to high levels of stress.

Herbert Freudenberger, a psychologist, coined the word “burnout” in 1974. While burnout is recognized as a valid medical illness, brain fog is not. Individuals suffering from burnout almost invariably exhibit symptoms of brain fog.

Burnout is frequently connected with a particular career or line of employment. Whether you labor for pay or volunteer, work outside the house or care for a family full-time, certain variables might increase your risk of burnout and related brain fog.

Mental burnout can be caused by high demands, a lack of personal control, and an imbalance between work and reward. Burnout happens when expectations, time, energy, and other sources of stress exceed available rest, recognition, and other incentives.

Burnout has a detrimental influence on all aspects of your life, including your profession, relationships, hobbies, and personal life.



If you can’t think clearly, you can’t do any job well. The more concentration required by your job, the more alert your brain must be – all the time.

While your work may not require the same level of concentration as an air traffic controller’s or require the same level of in-depth problem-solving as a marine in enemy territory, every job is critical in some way, especially those that entail direct interaction with vulnerable individuals.

Regrettably, high-pressure vocations such as nursing, counseling, and similar fields are the most likely to result in brain fog and catastrophic mental burnout. The best nootropics for brain fog can assist in maintaining your brain’s optimum condition, allowing you to perform effectively under pressure, after all, brain supplements are just that: brain health and mental function enhancing.


Brain fog episodes can result in breakdowns in communication among families and other intimate relationships. Long-term brain health has tremendous impacts. Constant obligations associated with managing and caring for a family might eventually result in mental burnout, particularly if you are the family’s lone homemaker or primary caregiver for an ailing family member.

And you can’t care about someone if you can’t count you your long-term brain health. 



The stresses associated with getting a college degree can significantly impact cognitive performance. The strain of late-night study sessions, major tests, and maintaining a high-grade point average can deplete mental vitality, resulting in periods of brain fog. This is especially true for students who use synthetic and simulating smart drugs. The best cognitive enhancer for studying, MAXIMUM MIND, can aid in providing a natural alternative and in improving brain functions associated with learning.

Academics is all about education, which cannot be accomplished with a cloudy head. Maintain a clear mind by obtaining adequate sleep, eating a balanced diet with the right amino acids, and taking the appropriate vitamins.

Personal Life

Even if you live alone and are single, everything functions more smoothly when your cognitive abilities are at their peak. At a minimum, brain fog may be inconvenient and time-consuming. Forgetting why you entered a room or repeatedly forgetting your keys adds up in terms of time and stress and is detrimental to long-term brain health.

Adulthood and its relationships demand focus, memory, and problem-solving abilities. With a clouded mind, none of it is possible. Maintain a clean head to ensure that your personal life goes as well as it should.


Your hobbies are both a source of inspiration and a creative outlet. They should be, at the very least. It’s challenging to be impassioned when one’s brain is clouded. Brain fog makes it more difficult to do daily tasks, including hobbies.

Whether your after-hours hobbies involve athletics, performance, crafts, or pretty much anything else, they all need concentration, proper brain function, memory, and critical thinking. Maintain a competitive edge by safeguarding your brain with natural cognitive enhancers.


Healthy Lifestyle Tips to Clear Brain Fog

“There is something to be said for keeping at a thing, isn’t there?” 
— Frank Sinatra

Brain fog and mental tiredness can last minutes or months and are caused by a variety of different circumstances. The key to resolving a problem is to go to its source.

Mental exhaustion is frequently the consequence of extended, intense concentration on a single task and significant levels of mental stress or emotional engagement. As with our bodies, our brains have a limit to the amount of work they can do and the amount of energy they can expend – and this limit varies by individual.

Mental exhaustion often occurs later in the day, when most of our mental energy has been spent on work, housework, studies, or other everyday responsibilities.

When our mental energy is spent, things become more challenging, the focus becomes more difficult, our attention wanders, and we become more prone to errors.

While certain factors that contribute to brain fog are beyond our control – such as menopause or neurological disorders – we can address most of them by altering our lifestyle choices.



If you have frequent sleep interruptions, you are more likely to wake up feeling fuzzy. Sleep is critical since it is when the brain generates and stores energy and repairs cells. Lack of sleep is terrible for brain fog. The more frequently sleep is disturbed, the longer the morning fog might last.

Getting adequate sleep enables your brain to replenish the energy used throughout the day and store it for the following day.

Although experts recommend six to eight hours of unbroken sleep, your brain’s requirements vary according to your age, metabolism, and overall health. And quantity is less important than sleep quality. Eight hours of restless sleep may actually be more tiring than five hours of uninterrupted, cyclical sleep.


Experts believe that stress is the most prevalent component in the majority of cognitive difficulties, and it has a variety of negative effects on the brain and brain cells, including brain fog. On the other hand, normal, ordinary stress should not result in brain fog. Unless you are experiencing extreme stress, such as the death of a loved one or the delivery of a newborn, you should explore other possible causes of frequent or severe brain fog.

Finding techniques to combat the impact of daily pressures by reducing stress in your daily life can assist.

Exercise, meditation, yoga, mindfulness, deep breathing, tai chi, and various other relaxing activities can help alleviate stress, enhance overall well-being, and prevent the onset of brain fog. The best nootropics for stress like MAXIMUM MIND can help reduce stress caused by day-to-day activities.



Glucose is the brain’s principal energy source, and fluctuations in glucose levels can result in short-term symptoms of brain weariness and diminished cognitive benefits. The frequency with which these episodes occur varies according to your level of control over your blood sugar levels.

A nutritious, whole-foods-based diet that is high in Omega 3, 6, and 9 fatty acids, magnesium, and methylated B vitamins will help boost brain energy and decrease your risk of mental weariness. Herbal supplements won’t hurt either.

The best nootropics for brain fog occasionally provide antioxidants that combat free radicals and are recommended to enhance cognitive performance by preserving the brain from free radical damage. Supplementing antioxidants via food and multivitamins may help alleviate some brain fog symptoms.


Depression can result in mental exhaustion, imbalance of brain chemicals, fogginess, and even clinical burnout. A sad brain becomes confused more easily and frequently, and depression is known to impair memory, attention, problem-solving, and mood.

If the underlying reason is identified, mental weariness can be controlled most of the time. By altering your lifestyle or habits, you may be able to reduce the frequency and intensity of foggy spells.

Ingredients-with-best-nootropics-for brain-fog-at-MARCO'S-GROUNDS-web

MAXIMUM MIND as the Best Nootropics for Brain Fog

“Good ideas come from bad ideas, but only if there are enough of them.” 
— Seth Godin

fried-egg-eggs-with-best-nootropics-for brain-fog-at-MARCO'S-GROUNDS-web


When it comes to natural nootropics, you can’t go wrong with citicoline. It is one of the most effective all-purpose brain boosters available for long-term brain health, making it one of the best nootropics for brain fog. Several clinical studies demonstrated that citicoline enhances mental vigor by increasing cerebral blood flow and shielding brain cells from free radical damage. This nootropic is so potent that it is used to help persons with neurological diseases or brain injuries improve their cognitive performance.

Citicoline increases acetylcholine levels, one of the major brain chemicals important in learning and memory. Additionally, it includes CDP choline, a component of phosphatidylcholine, a phospholipid that helps maintain the membranes of brain cells, protects memory, and enhances cerebral transmission.

Citicoline was found in a study in NMR in Biomedicine to effectively mitigate the symptoms of mental tiredness by increasing frontal lobe activity and brain energy reserves in research. [9]

However, excessive CDP choline might actually cause people to experience brain fog. The study cited before showed that subjects benefited more from a lesser dosage. The composition in MAXIMUM MIND provides the optimal quantity of Citicoline to improve mental vigor without overdoing it.

Note: there’s an effective dose of citicoline as Cognizin® in each dose of MAXIMUM MIND.

Read more about citicoline on the Marco’s Grounds Deep Dive and about the benefits of citicoline for brain power here.

cheese-with-best-nootropics-for brain-fog-at-MARCO'S-GROUNDS-web

N-Acetyl L-Tyrosine

Brain fog often occurs due to excessive oxidative stress and general stress placed on the brain by any of the causes described above. High-stress levels can deplete amino acid derivates called catecholamines such as dopamine and norepinephrine, which your brain needs to function properly.

Thus, when you’re under duress and have to meet a deadline or perform some major multitasking, chemical depletion and stress can compound, resulting in a downward cognitive cycle and paralyzing brain fog.

N-acetyl L-tyrosine (NALT), one of the best nootropics for brain fog, alleviates brain fog by increasing catecholamine levels in brain cells, assisting you in meeting stress-related demands, and safeguarding cognitive functioning.

According to animal studies, supplementation with the natural nootropics tyrosine reduces stress levels, increases catecholamine production, and protects from brain chemicals depletion. Further, a study found in National Academies Press asserts that this multidimensional method combats brain fog by protecting cognitive activities such as learning and working memory. [10]

Note: there’s an effective dose of L-tyrosine as NALT at 99% purity in each dose of MAXIMUM MIND.

Read more about N-acetyl-L-tyrosine on the Marco’s Grounds Deep Dive or find out more about the benefits of L-tyrosine for brain power here. 

vitamin-b12-cobalamin-rich-food-with-best-nootropics-for brain-fog-at-MARCO'S-GROUNDS-1920x1080-web

Methylated B Vitamins

Most people wouldn’t think of B vitamins as smart drugs. Yet, deficiency in B5, B6, B9, or B12 will cause serious neural imbalances that will prevent thinking altogether. B9, commonly known as folate or folic acid, is a B complex vitamin that acts in conjunction with B12. Both work in tandem to ensure that brain cells operate normally and are protected from free radical damage and oxidative stress.

A study found in the Journal of Alzheimer’s Disease verifies that when combined, methylated B12 and B9 have been shown to boost memory and protect cognition by reducing homocysteine levels — a naturally occurring sulfuric amino acid thought to contribute to persistent mental tiredness and irreversible loss of associated cognitive processes. [11]

Are you aware? According to studies found in The Journal of Pain, increasing vitamin A and vitamin C consumption appears to enhance cognitive performance in people with brain fog, probably due to the antioxidant action of these vitamins on brain cells. [12]

Consider stacking MAXIMUM MIND with a high-quality, high-absorption multivitamin pill containing enough Vitamin A and C.

Note: there’s an effective dose of methylated vitamin B5, B6, B9 and B12 in each dose of MAXIMUM MIND.

Read more about methylated vitamin b12 on the Marco’s Grounds Deep Dive and why you should never consider non-methylated B vitamins.

ashwagandha-with-best-nootropics-for brain-fog-at-MARCO'S-GROUNDS-web

Organic Ashwagandha Root Extract

Ashwagandha, also known as “Indian Ginseng,” is an Ayurvedic Rasayana or medicinal plant (tonic). When it comes to mental and physical wellness, ashwagandha is thought to be a supplement that can help high achievers feel better physically and emotionally.

As one of the best nootropics for brain fog, ashwagandha can help relieve stress and anxiety by lowering cortisol, the stress hormone. Ashwagandha is considered an adaptogen plant and is classified under herbal supplements.

Ashwagandha improves cognition and memory and several brain processes, as well as the ability to perform day-to-day tasks, according to the Journal of Traditional, Complementary, and Alternative Medicines [13]. For that herbal supplements go, ashwagandha is certainly top-tier. 

Since it affects stress, the major cause of brain fog, ashwagandha is one of the best nootropics for brain fog.

Note: there’s an effective dose of organic ashwagandha full-spectrum root extract, standardized at 10% withanolides, and less than 1% withaferin A in each dose of MAXIMUM MIND.

Read more about ashwagandha on the Marco’s Grounds Deep Dive or dig deeper into the health benefits of ashwagandha here.

beetroot-with-best-nootropics-for brain-fog-at-MARCO'S-GROUNDS-web


The liver converts dietary uridine to uridine monophosphate, which is then excreted in the blood.

Uridine can be found in a wide range of foods. Supplementation as a dietary supplement may be necessary to reap the numerous outstanding benefits of uridine, particularly those related to cognition, which are primarily absorbed through diet.

Uridine as a dietary supplement has been found to easily penetrate the blood-brain barrier. Uridine must be converted into CDP choline in the brain which is necessary for proper acetylcholine levels. The latter is a neurotransmitter involved in memory, mood regulation, muscle control, and other brain and nervous system functions.

The combined effects of uridine promote and increase neuroplasticity, or the brain’s ability to reconstruct and adapt in response to learning and brain training, according to a study published in Nutrition Reviews [13]. A stress-reduction technique that is undeniably beneficial.

Because of its numerous benefits, uridine is one of the best nootropics for brain fog. By assisting in neurite regeneration, the primary process by which neurons develop into axons or dendrites.

Note: there’s an effective dose of uridine at 99% purity in each dose of MAXIMUM MIND.

Read more about uridine on the Marco’s Grounds Deep Dive or read more about the health benefits of uridine here.


Organic Bacopa Monnieri Leaf Extract 

For what natural nootropics go, it’s hard to go wrong with bacopa monnieri. It is a nootropic herb well known for its memory-enhancing properties, which also extend to learning and knowledge retention.

Bacopa monnieri is considered an adaptogen plant and is classified under herbal supplements. It appears to alleviate stress and increase acetylcholine levels; specifically. It also dampens brain chemicals that often surge in reaction to stress.

Along with dampening the production of stress hormones, it has been hypothesized that bacopa monnieri may promote “calming” brain chemicals, such as serotonin and GABA, which may further aid in stress relief and resistance. This makes bacopa monnieri a potent nootropic for brain fog as we’ve seen a major part of the latter comes due to stress.

The plant has been likened to anti-anxiety medications in animal experiments. Clinical studies appear to have made a big discovery about bacopa monnieri’s potential in this study: [15] Unlike anxiety medications, which relieved tension but also caused amnesia and motor impairments, bacopa monnieri relieved stress while increasing cognition. This is naturally great news for human brain health.
Note: there’s an effective dose of organic bacopa monnieri leaf extract at 50% minimum bacosides, in each dose of MAXIMUM MIND.

Read more on bacopa on the Marco’s Grounds Deep Dive or find out more about the health benefits of bacopa here.



L-theanine raises alpha brain waves to help relieve stress and keep your mind calm and clear. An Alpha brain wave mind-state has been called “awake relaxation.” 

The “stress-creating-more–stress” cycle hurts your brain power and makes you moody and blue and prone to brain fog, making it even more challenging to think straight. So, one of the best things you can do to get rid of stress-induced brain fog is just to relax. L-theanine is a unique nootropic that can help you do just that.

It is a natural amino acid that is one of the nootropics in green tea. It has a lot of beneficial bioactive effects, but the most interesting one is L-theanine’s ability to raise Alpha brain waves, which makes people feel calm, clear, and creative while they’re still awake and have great mental activity.

In brief, L-theanine’s Alpha brain wave enhancing action provides a direct and considerable “chill out” impact that aids in the reduction of stress.

A study in the Journal of Herbal Pharmacotherapy found that L-theanine also addresses stress directly through its soothing effect on brain chemicals and brain processes: evidence suggests it may aid in the stabilization of “agitating” neurotransmitters while increasing “relaxing” neurotransmitters. [16]

A human study in Biological Psychology indicates that L-theanine’s ability to calm excitable neurons is reflected in a reduced heart rate and decreased stress chemical indicators in human volunteers during high-stress mental performance tasks. [17]

Additionally, this natural nootropic provides additional benefits for stressed-out brains. 

L-theanine helps to alleviate the uneasiness and jitteriness associated with excessive caffeine usage.

If you get behind at work, you may begin drinking mugs of coffee in an attempt to increase attentiveness and catch up. The downside: all that extra caffeine places more strain on the body and mind and may result in the dreaded caffeine jitters, making optimal performance impossible.

L-theanine has been demonstrated to help alleviate the jittery adverse effects that might occur when caffeine is used.

As a result, L-theanine combined with caffeine is one of the most often utilized nootropic stacks.

The natural combination between L-theanine and caffeine also explains why drinking green tea is so popular: It creates a more lucid and attentive state of mind than that produced by highly caffeinated coffee. It’s pure brain power.

Green tea contains the coveted “Theanine + Caffeine” nootropic combination naturally.

Have you ever gone to bed stressed and awoke to feel sluggish and with a fuzzy brain? By promoting restful sleep quality, L-Theanine indirectly benefits other nootropics for stress. Stress can interrupt good sleep patterns by activating the sympathetic nervous system, which releases fight-or-flight stress hormones meant to keep you aware, awake, and alive – even when it’s time to sleep. 

The subsequent lack of quality sleep may increase stress, brain fog, sleep problems, and even health problems. Stress-induced vicious sleep cycles are difficult to interrupt and necessitate the use of a specialized sleep aid.

In clinical studies found in the Journal of the American College of Nutrition, L-theanine has been established to be a safe, natural, and effective sleep aid that may dramatically improve sleep quality. [18]

Unlike tranquilizing sleep aids, researchers are now discovering that L-theanine promotes sleep onset without sedation. This shows that L-theanine may assist you in waking up without the sluggish side effects associated with more potent sleep aids.

Healthy, restful sleep can contribute significantly to overall brain fog reduction, providing yet another layer of nutritional support for L-theanine’s nootropic activity.

Note: there’s an effective dose of L-theanine from organic green tea leaf extract in each dose of MAXIMUM MIND.

Read more about L-theanine on the Marco’s Grounds Deep Dive or find out the best caffeine and L-theanine combination here.


“Our greatest weakness lies in giving up. The most certain way to succeed is always to try just one more time.”
— Thomas Edison

The causes of brain fog are pretty much rooted in how we live our lives. However, we must take these into consideration and supplement them as much as possible for increased cognitive benefits as well as general health benefits.

MAXIMUM MIND combines many of the best nootropics for brain fog into a single, pure, and healthy universal stack that is stimulant-free as well.

The innovative nootropic design of MAXIMUM MIND goes beyond conventional smart medications, vitamins, and brain pills to enhance cognitive performance and brain power.

The components in this advanced combination include nootropics for brain fog that have been chosen for their capacity to maintain the mental function of the human brain under duress and protect the brain from stress-related burnout.

A premium dietary supplement like MAXIMUM MIND helps alleviate the numerous unpleasant symptoms associated with brain fog while fueling the brain for increased resilience to burnout and enhanced long-term cognitive fitness.

Why not benefit from the best nootropics for brain fog in their purest form along with other clinically studied compounds for increasing brain performance and health with MAXIMUM MIND?


Clinically Studied

Pharmaceutical Grade Cognitive and Mind Enhancing Complex
Made in Switzerland


  1. Yelland GW. Gluten-induced cognitive impairment (“brain fog”) in coeliac. J Gastroenterol Hepatol. 2017 Mar;32 Suppl 1:90-93.

  2. Ocon AJ. Caught in the thickness of brain fog: exploring the cognitive symptoms of Chronic Fatigue Syndrome. Front. Physiol., 05 April 2013.

  3. Radley JJ et al. Repeated Stress Induces Dendritic Spine Loss in the Rat Medial Prefrontal Cortex. Cerebral Cortex, Volume 16, Issue 3, 1 March 2006, Pages 313–320

  4. Roozendal B, McEwan B, Chattarji S. Stress, memory and the amygdala. Nature Reviews Neuroscience. 2019. Volume 10, pages 423–433.

  5. Savic I. Structural Changes of the Brain in Relation to Occupational Stress. Cerebral Cortex. Volume 25, Issue 6. 1 June 2015. Pages 1554–1564.

  6. Michel A. Burnout and the Brain. Association for Psychological Science. Feb 2016.

  7. Schmaling, K. B., & Betterton, K. L. (2016). Neurocognitive complaints and functional status among patients with chronic fatigue syndrome and fibromyalgia. Quality of life research: an international journal of quality of life aspects of treatment, care, and rehabilitation, 25(5), 1257–1263.

  8. Choi, W., Lim, M., Kim, J. S., Kim, D. J., & Chung, C. K. (2015). Impaired pre-attentive auditory processing in fibromyalgia: A mismatch negativity (MMN) study. Clinical neurophysiology: official journal of the International Federation of Clinical Neurophysiology, 126(7), 1310–1318.

  9. Silveri MM et al. Citicoline enhances frontal lobe bioenergetics as measured by phosphorus magnetic resonance spectroscopy. NMR in Biomedicine. 24 Sep 2008.

  10. Lieberman HR. Tyrosine and Stress: Human and Animal Studies. Food Components to Enhance Performance: An Evaluation of Potential Performance-Enhancing Food Components for Operational Rations. Institute of Medicine Committee on Military Nutrition Research; Marriott BM, editor. Washington DC: National Academies Press. 1994.

  11. Shen L, Ji, HF. Associations between Homocysteine, Folic Acid, Vitamin B12, and Alzheimer’s Disease: Insights from Meta-Analyses. Journal of Alzheimer’s Disease. Vol. 46, no. 3. 2015. pp. 777-790.

  12. Bell, T., Shelley-Tremblay, J., & Pope, C. (2018). The impact of daily vitamin intake on brain fog in fibromyalgia. The Journal of Pain, 19(3), S102.

  13. Singh, N., Bhalla, M., de Jager, P., & Gilca, M. (2011). An overview of Ashwagandha: a Rasayana (rejuvenator) of Ayurveda. African Journal of Traditional, Complementary and Alternative Medicines, 8(5S).

  14. Wurtman, R. J., Cansev, M., Sakamoto, T., & Ulus, I. (2010). Nutritional modifiers of aging brain function: use of uridine and other phosphatide precursors to increase the formation of brain synapses. Nutrition reviews, 68(suppl_2), S88-S101.

  15. Bhattacharya, S. K., & Ghosal, S. (1998). Anxiolytic activity of a standardized extract of Bacopa monniera: an experimental study. Phytomedicine: international journal of phytotherapy and phytopharmacology, 5(2), 77–82.

  16. Nathan PJ, Lu K, Gray M, Oliver C. The neuropharmacology of L-theanine(N-ethyl-L-glutamine): a possible neuroprotective and cognitive enhancing agent. J Herb Pharmacother. 2006;6:21–30.

  17. Kimura K. L-Theanine reduces psychological and physiological stress responses. Biol Psychol. 2007 Jan;74(1):39-45.

  18. Rao, T. P., Ozeki, M., & Juneja, L. R. (2015). In Search of a Safe Natural Sleep Aid. Journal of the American College of Nutrition, 34(5), 436–447.

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